Making it different than past releases however, is the fact that you can install the game as many times as you want, on any amount of PCs. You will need to activate the game online, however, as well as keep Disc 1 in your drive at all times to play the game. If you happen to upgrade your motherboard or even videocard, the game will need to be reactivated.
As with all games that come with SecuROM, Rockstar notes you will not be able to remove the DRM completely from the PC, even after an uninstall. "Some traces will remain," says the developer, however "we are currently working with SecuROM to post information on our support pages regarding how to remove these inactive traces of the program for users who wish to do so."
Rockstar also noted that all versions of the game will include the DRM, including the online downloads from Steam.